eHeatmap of gene expression profiles of human ESCC cases (
n = 90) from TCGA database.
fPearson correlation analysis shows tight association of CCL2 with CCR2 and PD-1.
gGene set enrichment analysis (GSEA) between group high (
n = 52) and low (
n = 38) of CCL2 expression shows enriched pathways associated with PD-1 signaling.
hHeatmap shows that expression of PD-1 signaling pathway associated genes is correlated with CCL2 expression in human ESCC